SCHEMBL8632079

SCHEMBL8632079

ClC(Cl)=CCOc1ccc(Sc2ccc(Cl)cc2)cc1Br

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
NPC1 O15118 6/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
LMNA P02545 3/20 0.37
RAB9A P51151 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GAA P10253 2/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.34
PPARD Q03181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632449 0.89 HTT (0.41) MAPTALDH1A1PKMHPGDNPC1
SCHEMBL8635615 0.89 MAPT (0.39) MAPTALDH1A1PKMHPGDNPC1
SCHEMBL8636014 0.85 POLB (0.43) MAPTALDH1A1PKMHPGDNPC1
SCHEMBL8632153 0.83 PLAU (0.35) MAPTALDH1A1PKMHPGDNPC1
SCHEMBL8632579 0.80 NPC1 (0.38) MAPTALDH1A1HPGDNPC1MAOA
SCHEMBL8633981 0.73 EPAS1 (0.38) MAPTALDH1A1PKMNPC1LMNA
SCHEMBL8631583 0.73 NPC1 (0.41) MAPTALDH1A1HPGDNPC1LMNA
SCHEMBL8633461 0.71 PPARG (0.39) MAPTNPC1MAOBLMNASMN1; SMN2
SCHEMBL2348650 0.70 MAPT (0.35) MAPTSMN1; SMN2
SCHEMBL8633861 0.68 MAOA (0.44) MAPTALDH1A1HPGDNPC1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed