Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629421 | 0.86 | CA12 (0.47) | F10KMT2APRSS1F2 | |
| SCHEMBL7779453 | 0.85 | CA1 (0.61) | POLBMAPTKMT2A | |
| SCHEMBL8632840 | 0.82 | LRRK2 (0.42) | F10 | |
| SCHEMBL8632289 | 0.81 | AKR1B1 (0.40) | F10 | |
| SCHEMBL8632961 | 0.80 | F10 (0.40) | F10 | |
| SCHEMBL8628206 | 0.80 | PTGES2 (0.39) | — | |
| SCHEMBL8632216 | 0.80 | SCN9A (0.46) | F10MAPTKMT2AF2 | |
| SCHEMBL8631181 | 0.79 | PTGS2 (0.50) | — | |
| SCHEMBL8634768 | 0.79 | F10 (0.42) | F10 | |
| SCHEMBL8627977 | 0.79 | PTGS2 (0.50) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |