SCHEMBL863235

SCHEMBL863235

Cc1ccnc(-c2ccc(-c3ccc(F)cc3F)[nH]2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 1/20 0.45
THRB P10828 1/20 0.45
HPGD P15428 1/20 0.45
CCR1 P32246 1/20 0.44
CCR5 P51681 1/20 0.44
CCR8 P51685 1/20 0.44
KMO O15229 1/20 0.39
METAP2 P50579 1/20 0.38
NPC1 O15118 2/20 0.37
ALOX15 P16050 2/20 0.37
RAB9A P51151 2/20 0.37
KIT P10721 2/20 0.37
HCRTR1 O43613 2/20 0.36
HCRTR2 O43614 2/20 0.36
KDM4A O75164 1/20 0.36
KDM5A P29375 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
KDM5B Q9UGL1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503953 0.83 CCR1 (0.55) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL29766750 0.83 CCR1 (0.55) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL16910413 0.83 CCR1 (0.55) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL6130712 0.79 CCR1 (0.50) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL6130738 0.79 CCR1 (0.50) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL6130746 0.79 CCR1 (0.50) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL29766780 0.78 CCR1 (0.48) MEN1KMT2AALDH1A1THRBHPGD
SCHEMBL13977313 0.76 JAK2 (0.54) KMOKITJAK2CDK1CCNA2
SCHEMBL13977719 0.74 JAK2 (0.58) JAK2CDK1CCNA2CDK2CCNA1
SCHEMBL14125000 0.70 CCR1 (0.74) MEN1KMT2ACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507679-B2 Heteroleptic, dual tridentate Ru(II) complexes as sensitizers for dye-sensitized solar cells NATIONAL TSING HUA UNIVERSITY (TW) 2013-08-13 US disclosed
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS NATIONAL TSING HUA UNIVERSITY (TW) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120073660-A1 HETEROLEPTIC, DUAL TRIDENTATE RU(II) COMPLEXES AS SENSITIZERS FOR DYE-SENSITIZED SOLAR CELLS RUVBL2, RUVBL1, CCNL2 MEN1 2006/4885KMT2A 2143/4885ALDH1A1 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.