SCHEMBL503953

SCHEMBL503953

Cc1ccnc(-c2ccc(F)cc2F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.55
CCR5 P51681 1/20 0.55
CCR8 P51685 1/20 0.55
KMO O15229 2/20 0.49
KDM1A O60341 3/20 0.45
HDAC1 Q13547 3/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HCRTR1 O43613 2/20 0.44
HCRTR2 O43614 2/20 0.44
DHODH Q02127 1/20 0.43
CYP2A6 P11509 1/20 0.41
METAP2 P50579 1/20 0.41
UHRF1 Q96T88 1/20 0.41
ABL1 P00519 1/20 0.40
BCR P11274 1/20 0.40
FAAH O00519 1/20 0.40
F2RL3 Q96RI0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766750 1.00 CCR1 (0.55) CCR1CCR5CCR8KMOKDM1A
SCHEMBL16910413 1.00 CCR1 (0.55) CCR1CCR5CCR8KMOKDM1A
SCHEMBL6130746 0.95 CCR1 (0.50) CCR1CCR5CCR8KMOKDM1A
SCHEMBL6130712 0.95 CCR1 (0.50) CCR1CCR5CCR8KMOKDM1A
SCHEMBL6130738 0.95 CCR1 (0.50) CCR1CCR5CCR8KMOKDM1A
SCHEMBL29766780 0.94 CCR1 (0.48) CCR1CCR5CCR8KMOKDM1A
SCHEMBL29445848 0.85 KMO (0.54) KMOKDM1AFAAHMEN1KMT2A
SCHEMBL19072696 0.85 KMO (0.54) KMOKDM1AFAAHMEN1KMT2A
SCHEMBL863235 0.83 MEN1 (0.45) CCR1CCR5CCR8KMOKDM1A
SCHEMBL4509227 0.80 CCR1 (0.57) CCR1CCR5CCR8HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114891043-B Preparation method of cationic iridium (III) complex 昆明贵金属研究所 2024-04-26 CN claimed
CN-114891043-A Preparation method of cationic iridium (III) complex 昆明贵金属研究所 2022-08-12 CN claimed
CN-114361355-A Top-emission green organic electroluminescent device and preparation method thereof 中国科学院长春应用化学研究所 2022-04-15 CN claimed
CN-114361355-A Top-emission green organic electroluminescent device and preparation method thereof 中国科学院长春应用化学研究所 2022-04-15 CN disclosed
US-10236454-B2 Luminescent complexes and display devices UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2019-03-19 US disclosed
US-9929358-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-27 US disclosed
US-9929358-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-27 US disclosed
US-9929358-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-27 US disclosed
US-9859511-B2 Organoiridium complex for organic electroluminescent elements TANAKA KIKINZOKU KOGYO K.K. (JP) 2018-01-02 US disclosed
US-20170237021-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS TANAKA KIKINZOKU KOGYO K.K. (JP) 2017-08-17 US disclosed
US-9722191-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-01 US disclosed
US-20050048312-A1 Phosphorescent material LG CHEM, LTD. (KR) 2005-03-03 US disclosed
EP-1489111-A1 POLYMERIC COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KABUSHIKI KAISHA (JP) 2004-12-22 EP disclosed
EP-1484380-A1 POLYMERIC PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
EP-1484381-A1 PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
US-20040106006-A1 Phosphors, process for production thereof, phosphorescent compositions and articles made by using the same JSR CORPORATION (JP) 2004-06-03 US disclosed
US-20040091739-A1 Polymeric phosphorescent agent and production process thereof, and luminescent composition and applied products thereof JSR CORPORATION (JP) 2004-05-13 US disclosed
US-20030224208-A1 Polymer compound and electroluminescent element CANON KABUSHIKI KAISHA (JP) 2003-12-04 US disclosed
US-20020024293-A1 Light-emitting element and iridium complex FUJI PHOTO FILM CO., LTD. 2002-02-28 US disclosed
EP-1175128-A2 Light emitting element and azole compound FUJI PHOTO FILM CO., LTD. (JP) 2002-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10236454-B2 Luminescent complexes and display devices PAICS, ILK, NOD2 CCR1 1626/4885CCR5 544/4885CCR8 1164/4885
US-20170237021-A1 ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS L1CAM, ETFA, TTI2 CCR1 2320/4885CCR5 1832/4885CCR8 2630/4885
US-20020024293-A1 Light-emitting element and iridium complex IK, INTS6, LAGE3 CCR1 3850/4885CCR5 4152/4885CCR8 4065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.