Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632559 | 0.87 | POLB (0.50) | POLBALOX5THRBALDH1A1MAPT | |
| SCHEMBL8633566 | 0.82 | TSHR (0.55) | POLBALOX5THRBALDH1A1MAPT | |
| SCHEMBL8636072 | 0.80 | ALOX5 (0.39) | POLBALOX5THRBALDH1A1MAPT | |
| SCHEMBL8631339 | 0.76 | POLB (0.70) | POLBALOX5THRBALDH1A1MAPT | |
| SCHEMBL8629960 | 0.74 | ALOX5 (0.42) | POLBALOX5ALDH1A1MAPTPKM | |
| SCHEMBL8635706 | 0.74 | MAPT (0.40) | POLBALOX5THRBALDH1A1MAPT | |
| SCHEMBL78451 | 0.73 | KDM4E (0.46) | POLBTHRBALDH1A1MAPTPKM | |
| SCHEMBL8659550 | 0.73 | POLB (0.50) | POLBALOX5ALDH1A1MAPTPKM | |
| SCHEMBL3061911 | 0.72 | TSHR (0.59) | THRBALDH1A1MAPTTSHRNPC1 | |
| Bromide SCHEMBL11628834 | 0.71 | KDM4E (0.44) | POLBTHRBALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |