Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634675 | 0.79 | TSHR (0.56) | ALOX5ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL5790031 | 0.79 | TSHR (0.52) | ALDH1A1TSHRMAPK1NPSR1MAPT | |
| SCHEMBL11067773 | 0.77 | ALOX5 (0.49) | ALOX5ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL78451 | 0.75 | KDM4E (0.46) | ALDH1A1TSHRNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL3061911 | 0.74 | TSHR (0.59) | ALDH1A1TSHRNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL11669014 | 0.74 | ALOX5 (0.46) | ALOX5ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL8632445 | 0.74 | POLB (0.46) | ALOX5ALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL13990259 | 0.74 | TSHR (0.41) | ALOX5ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL14641064 | 0.74 | ALDH1A1 (0.40) | ALOX5ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL13934475 | 0.74 | THRA (0.47) | ALOX5ALDH1A1TSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |