Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630284 | 0.90 | POLB (0.39) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL8629617 | 0.88 | ALDH1A1 (0.41) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL8636072 | 0.85 | ALOX5 (0.39) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL8748380 | 0.85 | POLB (0.38) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL8632233 | 0.82 | CETP (0.39) | ALDH1A1PKMTSHRPOLBALOX5 | |
| SCHEMBL8632586 | 0.80 | POLB (0.35) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL8632559 | 0.79 | POLB (0.50) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL1059031 | 0.76 | MAPT (0.46) | MAPTALDH1A1TSHRPOLB | |
| SCHEMBL8633566 | 0.74 | TSHR (0.55) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL8632445 | 0.74 | POLB (0.46) | MAPTALDH1A1PKMHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |