Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930296 | 0.84 | MEN1 (0.70) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL352886 | 0.82 | TSHR (0.68) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL976467 | 0.82 | TSHR (0.68) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL903110 | 0.79 | KMT2A (1.00) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL5533585 | 0.79 | L3MBTL1 (0.69) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL13501824 | 0.79 | KMT2A (0.69) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL27722453 | 0.79 | KMT2A (0.76) | GAAMEN1KMT2ATSHRHTT | |
| SCHEMBL316093 | 0.79 | KMT2A (0.76) | GAAMEN1KMT2ATSHRHTT | |
| Hydrochloric Acid SCHEMBL30684542 | 0.78 | KMT2A (0.97) | GAAMEN1KMT2ATSHRHTT | |
| Hydrochloric Acid SCHEMBL30684473 | 0.78 | KMT2A (0.97) | GAAMEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |