Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633054 | 0.91 | SMN1; SMN2 (0.41) | MEN1KMT2AARMAPTLMNA | |
| SCHEMBL8630518 | 0.89 | AR (0.43) | MEN1KMT2AARPTGS1PTGS2 | |
| SCHEMBL8635051 | 0.88 | SMN1; SMN2 (0.42) | MEN1KMT2AARPTGS1PTGS2 | |
| SCHEMBL8631648 | 0.87 | AR (0.41) | MEN1KMT2AARPTGS1PTGS2 | |
| SCHEMBL8628070 | 0.85 | MEN1 (0.43) | MEN1KMT2AKDM1AEDNRBEDNRA | |
| SCHEMBL8632284 | 0.85 | AR (0.40) | MEN1KMT2AARPTGS1PTGS2 | |
| SCHEMBL8634845 | 0.83 | PI4KB (0.38) | ARPTGS1PTGS2EDNRAHTT | |
| SCHEMBL8630029 | 0.81 | MEN1 (0.45) | MEN1KMT2AKDM1AEDNRBEDNRA | |
| SCHEMBL8631394 | 0.81 | AR (0.43) | MEN1KMT2AARPTGS2MAPT | |
| SCHEMBL8632801 | 0.80 | MEN1 (0.43) | MEN1KMT2AKDM1AEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |