Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | NAT1 | P18440 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634444 | 0.90 | SMN1; SMN2 (0.42) | MEN1KMT2AEDNRAMAPTPOLB | |
| SCHEMBL8628755 | 0.86 | EDNRB (0.44) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8629794 | 0.86 | SMN1; SMN2 (0.46) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8632683 | 0.85 | MEN1 (0.40) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8630029 | 0.85 | MEN1 (0.45) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8632801 | 0.84 | MEN1 (0.43) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8631666 | 0.84 | EDNRB (0.42) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8633218 | 0.84 | EDNRB (0.42) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8629761 | 0.83 | PTGS2 (0.48) | MEN1KMT2AEDNRBEDNRAKDM1A | |
| SCHEMBL8633160 | 0.83 | MEN1 (0.43) | MEN1KMT2AEDNRBEDNRAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |