Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128825 | 0.78 | CES1 (0.31) | GRM2 | |
| SCHEMBL8638001 | 0.78 | GRM2 (0.32) | GRM2 | |
| SCHEMBL8632539 | 0.76 | GRM2 (0.31) | GRM2 | |
| SCHEMBL8635143 | 0.73 | RAB9A (0.38) | GRM2 | |
| SCHEMBL8554501 | 0.73 | HTR2C (0.37) | — | |
| SCHEMBL8631154 | 0.72 | MRGPRX4 (0.40) | GRM2 | |
| SCHEMBL3670516 | 0.69 | CA12 (0.40) | — | |
| SCHEMBL8114811 | 0.66 | TLK2 (0.46) | — | |
| SCHEMBL2429783 | 0.65 | JUN (0.44) | — | |
| SCHEMBL8121964 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828746-A1 | NOVEL QUINOXALINE DIONE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037500-A1 | NOVEL QUINOXALINE DIONE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-11-28 | — | — | WO | disclosed |