SCHEMBL8632989

SCHEMBL8632989

Cc1ccc(P2Oc3c(cc(C)cc3C(C)(C)C)Cc3cc(C)cc(C(C)(C)C)c3O2)cc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CA2 P00918 1/20 0.33
POLB P06746 1/20 0.33
TYR P14679 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634557 0.90 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8908187 0.89 ALDH1A1 (0.32) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8636480 0.85 ALDH1A1 (0.31) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL11122271 0.82 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL10641000 0.78 SMN1; SMN2 (0.41) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL9298522 0.78 SMN1; SMN2 (0.37) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL9356376 0.78 SMN1; SMN2 (0.37) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL10039476 0.78 KIF11 (0.31)
SCHEMBL31072320 0.77 SMN1; SMN2 (0.36) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8631123 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5712403-A CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-27 US disclosed
US-5600032-A OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed