SCHEMBL8908187

SCHEMBL8908187

Cc1cc2c(c(C(C)(C)C)c1)OP(c1ccccc1)Oc1c(cc(C)cc1C(C)(C)C)C2.Cc1cc2c(c(C(C)(C)C)c1)OP(c1ccccc1)Oc1c(cc(C)cc1C(C)(C)C)C2.[Pd]

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CA2 P00918 1/20 0.32
POLB P06746 1/20 0.32
TYR P14679 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634557 0.99 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8632989 0.89 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8636480 0.88 ALDH1A1 (0.31) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL11122271 0.86 ALDH1A1 (0.33) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8631123 0.85
SCHEMBL8636490 0.84 CYP1A2 (0.33)
SCHEMBL8634112 0.81 CA1 (0.37) ALDH1A1CA2SMN1; SMN2
SCHEMBL12415275 0.81 CYP1A2 (0.31)
SCHEMBL13681574 0.80 CA2 (0.32) ALDH1A1CA2
SCHEMBL10627261 0.78 ALDH1A1 (0.30) ALDH1A1CA2POLBTYRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5600032-A OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed