Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713540 | 0.92 | TDP1 (0.53) | TDP1L3MBTL1TBXAS1MAPK1KMT2A | |
| SCHEMBL9733099 | 0.89 | TBXAS1 (0.55) | TDP1L3MBTL1TBXAS1MAPK1KMT2A | |
| SCHEMBL7345369 | 0.85 | MMP8 (0.52) | TBXAS1MAPK1KMT2APKMNAPRT | |
| SCHEMBL10618105 | 0.83 | LMNA (0.43) | TDP1L3MBTL1TBXAS1KMT2APKM | |
| SCHEMBL10713534 | 0.82 | CHRNA7 (0.54) | TDP1L3MBTL1TBXAS1 | |
| SCHEMBL3949678 | 0.82 | MMP8 (0.54) | TDP1TBXAS1KMT2APKMNAPRT | |
| SCHEMBL11427624 | 0.82 | TDP1 (0.51) | TDP1L3MBTL1TBXAS1TSHR | |
| SCHEMBL10399164 | 0.82 | TDP1 (0.51) | TDP1L3MBTL1TBXAS1 | |
| SCHEMBL10399165 | 0.82 | TDP1 (0.51) | TDP1L3MBTL1TBXAS1 | |
| SCHEMBL6646153 | 0.81 | NAMPT (0.47) | TDP1L3MBTL1MAPK1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |