Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990302 | 0.85 | EGFR (0.39) | NR3C2MAOBFFAR4FFAR1L3MBTL1 | |
| SCHEMBL8990299 | 0.85 | EGFR (0.39) | NR3C2MAOBFFAR4FFAR1L3MBTL1 | |
| SCHEMBL8635263 | 0.76 | ADORA1 (0.38) | CCNA2CDK2PLK1CCNA1ALDH1A1 | |
| SCHEMBL8633321 | 0.72 | MAPT (0.31) | ALDH1A1MAPT | |
| SCHEMBL8634113 | 0.70 | IDO1 (0.44) | MAOB | |
| SCHEMBL8634117 | 0.70 | IDO1 (0.44) | MAOB | |
| SCHEMBL8637305 | 0.68 | USP2 (0.38) | CCNA2CDK2L3MBTL1ALDH1A1GAA | |
| SCHEMBL4382642 | 0.65 | TACR1 (0.48) | MAOBL3MBTL1ALDH1A1NR4A2MAPT | |
| SCHEMBL4410979 | 0.65 | MEN1 (0.48) | MAOBFFAR4FFAR1NR4A2MAPT | |
| SCHEMBL4395452 | 0.64 | FAAH (0.63) | ALDH1A1GAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |