SCHEMBL8633068

SCHEMBL8633068

Oc1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.49
LTA4H P09960 2/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
ESRRA P11474 3/20 0.46
PDK2 Q15119 1/20 0.45
MGLL Q99685 1/20 0.43
TSHR P16473 1/20 0.43
THRA P10827 2/20 0.41
THRB P10828 2/20 0.41
AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632090 0.97 AR (0.47) ARLTA4HNR1H2BAXESRRA
SCHEMBL8633991 0.92 HSD17B1 (0.47) ARLTA4HNR1H2BAXESRRA
SCHEMBL16648399 0.91 ESRRA (0.49) ARESRRATHRATHRB
SCHEMBL8636220 0.89 HSD17B1 (0.46) ARNR1H2ESRRATHRATHRB
SCHEMBL8632004 0.86 AR (0.47) ARESRRA
SCHEMBL8635974 0.86 ESRRA (0.46) ARLTA4HESRRATHRATHRB
SCHEMBL8636487 0.85 THRA (0.46) ARLTA4HTHRATHRB
SCHEMBL8636426 0.84 ESRRA (0.45) ARESRRA
SCHEMBL8635438 0.84 LTA4H (0.50) ARLTA4HESRRA
SCHEMBL8633891 0.83 SMN1; SMN2 (0.50) ARESRRATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed