Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690284 | 0.91 | KIF11 (0.50) | KIF11SLC6A11SLC6A1KCNH2MEN1 | |
| SCHEMBL4924705 | 0.89 | KIF11 (0.59) | KIF11SLC6A1KCNH2 | |
| SCHEMBL4931427 | 0.89 | KIF11 (0.59) | KIF11SLC6A1KCNH2 | |
| SCHEMBL4924692 | 0.89 | KIF11 (0.59) | KIF11SLC6A1KCNH2 | |
| SCHEMBL3689536 | 0.86 | KIF11 (0.50) | KIF11SLC6A11SLC6A1KCNH2 | |
| SCHEMBL3700947 | 0.86 | KIF11 (0.50) | KIF11SLC6A11SLC6A1KCNH2 | |
| SCHEMBL27081312 | 0.86 | KIF11 (0.50) | KIF11KCNH2MEN1KMT2A | |
| SCHEMBL16472146 | 0.86 | KIF11 (0.50) | KIF11KCNH2MEN1KMT2A | |
| SCHEMBL3695302 | 0.85 | SLC6A11 (0.48) | KIF11SLC6A11SLC6A1MEN1TP53 | |
| SCHEMBL5604514 | 0.85 | SLC6A11 (0.49) | KIF11SLC6A11SLC6A1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684954-B1 | NUCLEIC ACID PROBES CHEMICALLY 5'(OH)- AND/OR 3'(OH)-MODIFIED FOR INSERTING ONE OR MORE NON-RADIOACTIVE LABELING ELEMENTS THEREAT, AND METHOD FOR PREPARING SAME | WALLONE REGION (BE) | 1998-07-22 | — | — | EP | disclosed |