Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627187 | 0.92 | AVPR2 (0.40) | AVPR2MAPTTP53KMT2A | |
| SCHEMBL8627398 | 0.89 | AVPR2 (0.37) | AVPR2MAPTLMNAKMT2AHTT | |
| SCHEMBL8634667 | 0.88 | AVPR2 (0.51) | AVPR2MAPTPDK1PDK2PDK3 | |
| SCHEMBL8633374 | 0.85 | AVPR2 (0.52) | AVPR2MAPTPDK1PDK2PDK3 | |
| SCHEMBL8629474 | 0.84 | AVPR2 (0.51) | AVPR2MAPTPDK1PDK2PDK3 | |
| SCHEMBL8630162 | 0.83 | TSHR (0.38) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL8627536 | 0.82 | KCNMA1 (0.35) | MAPTLMNATP53KMT2AHTT | |
| SCHEMBL8634668 | 0.81 | AVPR2 (0.51) | AVPR2MAPTPDK1PDK2PDK3 | |
| SCHEMBL8630766 | 0.79 | AVPR2 (0.41) | AVPR2MAPTTP53KMT2A | |
| SCHEMBL8627190 | 0.77 | AVPR2 (0.42) | AVPR2MAPTTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |