Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627536 | 0.92 | KCNMA1 (0.35) | ALDH1A1MAPTLMNAMEN1HTT | |
| SCHEMBL8633371 | 0.89 | AVPR2 (0.49) | AVPR2MAPTLMNAHTTKMT2A | |
| SCHEMBL8630678 | 0.88 | AVPR2 (0.38) | AVPR2RAB9APAX8RECQLALDH1A1 | |
| SCHEMBL8627401 | 0.86 | AVPR2 (0.39) | AVPR2RAB9APAX8RECQLALDH1A1 | |
| SCHEMBL8627677 | 0.85 | AVPR2 (0.38) | AVPR2RAB9APAX8RECQLALDH1A1 | |
| SCHEMBL8627187 | 0.82 | AVPR2 (0.40) | AVPR2MAPTKMT2A | |
| SCHEMBL8630680 | 0.82 | AVPR2 (0.38) | AVPR2RAB9APAX8RECQLALDH1A1 | |
| SCHEMBL8629506 | 0.80 | KCNMA1 (0.36) | PAX8ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8627538 | 0.78 | KCNMA1 (0.36) | ALDH1A1MAPTLMNAMEN1HTT | |
| SCHEMBL8634463 | 0.77 | KMT2A (0.35) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |