Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628426 | 0.92 | LMNA (0.44) | CHRM5CHRM1CHRM3AVPR2GRM4 | |
| SCHEMBL8632058 | 0.90 | ALDH1A1 (0.43) | CHRM5CHRM1CHRM3AVPR2GRM4 | |
| Hydrochloric Acid SCHEMBL8631929 | 0.86 | AVPR2 (0.51) | CHRM5CHRM1CHRM3AVPR2LMNA | |
| Hydrochloric Acid SCHEMBL8634036 | 0.83 | AVPR2 (0.51) | CHRM5CHRM1CHRM3AVPR2LMNA | |
| SCHEMBL4685266 | 0.82 | AVPR2 (0.51) | CHRM5CHRM1CHRM3AVPR2GRM4 | |
| Hydrochloric Acid SCHEMBL8661678 | 0.82 | AVPR2 (0.52) | CHRM5CHRM1CHRM3AVPR2LMNA | |
| SCHEMBL8632070 | 0.82 | GRM4 (0.40) | CHRM5CHRM1CHRM3AVPR2GRM4 | |
| SCHEMBL8632575 | 0.81 | AVPR2 (0.46) | CHRM5CHRM1CHRM3AVPR2LMNA | |
| SCHEMBL8631926 | 0.81 | AVPR2 (0.44) | CHRM5CHRM1CHRM3AVPR2GRM4 | |
| SCHEMBL8630591 | 0.80 | AVPR2 (0.48) | CHRM1AVPR2HSD17B10MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |