Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688303 | 0.84 | AVPR2 (0.48) | GRM4AVPR2CHRM1AVPR1AABCB11 | |
| SCHEMBL8633396 | 0.82 | CHRM5 (0.41) | GRM4HSD17B10TP53LMNAAVPR2 | |
| SCHEMBL8632058 | 0.82 | ALDH1A1 (0.43) | GRM4HSD17B10TP53LMNAAVPR2 | |
| SCHEMBL8628426 | 0.81 | LMNA (0.44) | GRM4HSD17B10TP53LMNAAVPR2 | |
| SCHEMBL4688309 | 0.81 | AVPR2 (0.41) | GRM4HSD17B10AVPR2KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8631929 | 0.78 | AVPR2 (0.51) | TP53LMNAAVPR2KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8630791 | 0.77 | GRM4 (0.41) | GRM4HSD17B10TP53LMNAAVPR2 | |
| SCHEMBL8631926 | 0.77 | AVPR2 (0.44) | GRM4HSD17B10TP53LMNAAVPR2 | |
| SCHEMBL8632028 | 0.76 | GRM4 (0.41) | GRM4HSD17B10TP53LMNAAVPR2 | |
| SCHEMBL8628615 | 0.76 | GRM4 (0.40) | GRM4HSD17B10TP53LMNAAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |