Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.51 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4398412 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2THRATHRBDNM1 | |
| Bromide SCHEMBL31071683 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2THRATHRBDNM1 | |
| Bromide SCHEMBL31071682 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2THRATHRBDNM1 | |
| Bromide SCHEMBL31071676 | 1.00 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2THRATHRBDNM1 | |
| SCHEMBL27594490 | 0.91 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2THRATHRBDNM1 | |
| Hydrochloric Acid SCHEMBL15271262 | 0.89 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2THRATHRBDNM1 | |
| SCHEMBL176022 | 0.83 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2THRATHRBALDH1A1 | |
| Toluene SCHEMBL27653727 | 0.77 | TGM2 (0.40) | ZDHHC20ZDHHC2THRATHRBALDH1A1 | |
| Sulfuric Acid SCHEMBL27766767 | 0.76 | ZDHHC20 (0.36) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL27678348 | 0.76 | DNM1 (0.44) | DNM1ALDH1A1ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830616-A | ANTISTATIC AGENTS IS A QUATERNARY AMMONIUM COPOLYMER | IWATSU ELECTRIC CO., INC. (JP) | 1998-11-03 | — | — | US | disclosed |