Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633484 | 1.00 | BCHE (0.32) | BCHEACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8634627 | 0.82 | — | — | |
| SCHEMBL8633330 | 0.81 | MGMT (0.40) | NPC1RAB9ASMN1; SMN2DCPS | |
| SCHEMBL8633331 | 0.81 | MGMT (0.40) | NPC1RAB9ASMN1; SMN2DCPS | |
| SCHEMBL8637680 | 0.66 | — | — | |
| SCHEMBL8990377 | 0.66 | ADORA1 (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8990371 | 0.66 | ADORA1 (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14506041 | 0.62 | ALOX12 (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1266328 | 0.60 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8634448 | 0.60 | LMNA (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |