SCHEMBL8633546

SCHEMBL8633546

O=C(O)Nc1ccccc1S(=O)(=O)c1ncccc1C1=NOCCO1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 3/20 0.33
MEN1 O00255 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
PABPC1 P11940 1/20 0.31
EIF4H Q15056 1/20 0.31
TDP2 O95551 1/20 0.31
NPY5R Q15761 2/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8630714 0.87 CA1 (0.34) MEN1RAB9AKMT2ANPC1CA12
SCHEMBL8633092 0.81 CA1 (0.33) MEN1RAB9AKMT2ANPC1CA12
SCHEMBL8633120 0.79 TAAR1 (0.34) KMT2ACA1CA2KDM4EALDH1A1
SCHEMBL8629616 0.77 NPC1 (0.33) RAB9ANPC1CA12CA1CA2
SCHEMBL3783324 0.76 TDP1 (0.32) MEN1KMT2ATDP2KDM4EALDH1A1
SCHEMBL7908092 0.73 TDP2 (0.32) MEN1KMT2ATDP2GAA
SCHEMBL3776593 0.73 CA1 (0.33) MEN1KMT2ACA12CA1CA2
SCHEMBL10792948 0.72 CA2 (0.46) SLC40A1MEN1RAB9AKMT2ANPC1
SCHEMBL8653023 0.71 CA2 (0.32) KMT2ACA12CA1CA2CA9
SCHEMBL15805494 0.70 GAA (0.40) MEN1RAB9AKMT2ANPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847126-A N-azinyl-N'-(het) arylsulphonyl-ureas BAYER AKTIENGESELLSCHAFT (DE) 1998-12-08 US disclosed
US-5696257-A INTERMEDIATES FOR HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
US-5580842-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-03 US disclosed
US-5476936-A Herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-12-19 US disclosed