Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631669 | 0.90 | PTGES2 (0.38) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8634661 | 0.90 | PTGS2 (0.45) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8631591 | 0.88 | PTGS2 (0.41) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8632230 | 0.88 | PTGS2 (0.37) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8633695 | 0.87 | F10 (0.39) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL7772814 | 0.86 | PTGS2 (0.48) | PTGS2CA1CA2CA4CA9 | |
| SCHEMBL8634745 | 0.83 | PTGS2 (0.38) | PTGS2F10CA1CA2CA4 | |
| SCHEMBL8631787 | 0.83 | PTGS2 (0.40) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8633375 | 0.83 | F10 (0.37) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8632921 | 0.83 | PTGS2 (0.46) | PTGS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |