Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632274 | 0.88 | F10 (0.40) | F10F2 | |
| SCHEMBL8628225 | 0.87 | F10 (0.41) | F10F2 | |
| SCHEMBL8632661 | 0.86 | PTGS2 (0.44) | F10F2 | |
| SCHEMBL7778210 | 0.84 | MAPKAPK2 (0.54) | MAPKAPK2 | |
| SCHEMBL8629935 | 0.83 | PTGS2 (0.53) | F10 | |
| SCHEMBL8629361 | 0.82 | TGFBR1 (0.53) | F10F2SCN9AMAPKAPK2 | |
| SCHEMBL8631626 | 0.80 | ALOX5AP (0.43) | F10F2 | |
| SCHEMBL8631931 | 0.80 | MEN1 (0.49) | F10F2SCN9AMAPKAPK2 | |
| SCHEMBL7773338 | 0.78 | PTGS2 (0.50) | — | |
| SCHEMBL8629426 | 0.78 | F10 (0.47) | F10F2SCN9AMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |