Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637404 | 0.76 | FLT1 (0.51) | SMN1; SMN2CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL27182311 | 0.75 | PKM (0.64) | ALOX5PKMMEN1KMT2AALDH1A1 | |
| SCHEMBL10802488 | 0.73 | CYP3A4 (0.62) | ALOX5PKMSMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL10483661 | 0.73 | CYP3A4 (0.57) | ALOX5PKMSMN1; SMN2CYP3A4MEN1 | |
| Dimethylamine SCHEMBL8636090 | 0.72 | MAPT (0.40) | ALOX5SMN1; SMN2CYP3A4MEN1KMT2A | |
| SCHEMBL10717783 | 0.71 | PKM (0.59) | PKMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL267054 | 0.70 | ALOX5 (0.61) | ALOX5PKMSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10716338 | 0.70 | PKM (0.57) | PKMMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13600434 | 0.70 | ALOX5 (0.57) | ALOX5SMN1; SMN2CYP3A4MEN1KMT2A | |
| SCHEMBL31148954 | 0.70 | SMN1; SMN2 (0.57) | ALOX5PKMSMN1; SMN2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750782-A | ANTICARCINOGENIC AGENTS, ANTIHYPOXIC AGENTS, PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |