Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522089 | 0.73 | CYP3A4 (0.52) | MAPTATMCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8633723 | 0.72 | ALOX5 (0.47) | MAPTCYP3A4SMN1; SMN2ALDH1A1ALOX5 | |
| SCHEMBL9679015 | 0.68 | ALDH1A1 (0.49) | MAPTATMCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9557653 | 0.68 | ALDH1A1 (0.50) | ATMSMN1; SMN2ALDH1A1ALOX5RAB9A | |
| SCHEMBL10033454 | 0.67 | CYP3A4 (0.57) | CYP3A4SMN1; SMN2ALDH1A1ALOX5RAB9A | |
| SCHEMBL13600434 | 0.67 | ALOX5 (0.57) | MAPTCYP3A4SMN1; SMN2ALDH1A1ALOX5 | |
| SCHEMBL10483661 | 0.67 | CYP3A4 (0.57) | MAPTCYP3A4SMN1; SMN2ALDH1A1ALOX5 | |
| SCHEMBL9678216 | 0.67 | ALDH1A1 (0.45) | MAPTATMCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9186012 | 0.67 | PKM (0.51) | MAPTATMALDH1A1ALOX5LMNA | |
| Dimethylamine SCHEMBL10717788 | 0.66 | PKM (0.57) | MAPTALDH1A1ALOX5LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750782-A | ANTICARCINOGENIC AGENTS, ANTIHYPOXIC AGENTS, PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |