SCHEMBL8633865

SCHEMBL8633865

CCCc1cc(Oc2ccc(C3CCCCC3)cc2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.43
PPARA Q07869 4/20 0.40
PPARD Q03181 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635798 0.90 PPARG (0.43) PPARGPPARAPPARD
SCHEMBL8632261 0.82 PPARG (0.43) PPARGPPARAPPARD
SCHEMBL8636876 0.80 PTGDR2 (0.36) PPARGPPARA
SCHEMBL8632253 0.79 PPARG (0.40) PPARGPPARAPPARD
SCHEMBL8633668 0.79 PTGDR2 (0.35) PPARGPPARA
SCHEMBL8632434 0.77 EPHX2 (0.42) PPARG
SCHEMBL8636070 0.75 PPARG (0.47) PPARGPPARAPPARD
SCHEMBL8634634 0.74 LTB4R (0.42) PPARGPPARAPPARD
SCHEMBL8637054 0.73 HTT (0.40) PPARGPPARAPPARD
SCHEMBL8634705 0.73 LTA4H (0.43) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed