SCHEMBL8636070

SCHEMBL8636070

CCCc1cc(Oc2cccc(-c3ccccc3)c2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 17/20 0.47
PPARD Q03181 3/20 0.42
PPARA Q07869 9/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635702 0.89 PPARG (0.47) PPARGPPARDPPARAFFAR1FFAR4
SCHEMBL8634634 0.83 LTB4R (0.42) PPARGPPARDPPARALTB4RLTB4R2
SCHEMBL8632261 0.82 PPARG (0.43) PPARGPPARDPPARALTB4RLTB4R2
SCHEMBL8636192 0.81 FFAR4 (0.40) PPARDFFAR1FFAR4
SCHEMBL8632253 0.80 PPARG (0.40) PPARGPPARDPPARALTB4RLTB4R2
SCHEMBL8632777 0.79 FFAR4 (0.40) FFAR1FFAR4
SCHEMBL5208940 0.76 PPARG (0.48) PPARGPPARDPPARA
SCHEMBL8633865 0.75 PPARG (0.43) PPARGPPARDPPARA
SCHEMBL8637054 0.72 HTT (0.40) PPARGPPARDPPARAFFAR4LTB4R
SCHEMBL8634705 0.72 LTA4H (0.43) PPARGPPARDPPARALTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed