SCHEMBL8633892

SCHEMBL8633892

CCC1=NN(c2ccc(C(=O)O)cc2)C(=O)C1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHMT2 P34897 1/20 0.70
POLB P06746 4/20 0.57
GAA P10253 6/20 0.52
ALDH1A1 P00352 6/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 5/20 0.44
KDM4E B2RXH2 5/20 0.44
KAT8 Q9H7Z6 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 3/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM2 P08172 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6947831 0.92 SHMT2 (0.58) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL13597563 0.85 GAA (0.56) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL4620529 0.85 GAA (0.55) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL6953402 0.83 GAA (0.60) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL4319899 0.83 SHMT2 (1.00) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL4622034 0.82 GAA (0.53) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL4619249 0.82 SHMT2 (0.54) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL643536 0.80 POLB (0.75) POLBGAAALDH1A1L3MBTL1MEN1
SCHEMBL8428093 0.78 GAA (0.47) SHMT2POLBGAAALDH1A1L3MBTL1
SCHEMBL8427551 0.78 GAA (0.58) SHMT2POLBGAAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549486-B1 Microprecipitated methine oxonol filter dye dispersions EASTMAN KODAK CO (US) 1998-07-15 EP disclosed
US-5326687-A Photographic silver halide element containing microprecipitated methine oxonol filter dye dispersions EASTMAN KODAK COMPANY (US) 1994-07-05 US disclosed
US-5274109-A A pyrazole-based cyanine dye EASTMAN KODAK COMPANY (US) 1993-12-28 US disclosed
EP-0549486-A2 Microprecipitated methine oxonol filter dye dispersions EASTMAN KODAK COMPANY (US) 1993-06-30 EP disclosed