SCHEMBL8908019

SCHEMBL8908019

COc1cc2c(c(C(C)(C)C)c1)OPOc1c(cc(OC)cc1C(C)(C)C)C2

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
EGFR P00533 1/20 0.32
DRD2 P14416 1/20 0.32
DRD1 P21728 1/20 0.32
DRD5 P21918 1/20 0.32
DRD3 P35462 1/20 0.32
ALDH1A1 P00352 2/20 0.31
GAA P10253 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8631061 0.78 SMN1; SMN2 (0.39) CA2ALDH1A1CYP3A4
SCHEMBL8633940 0.78 ELANE (0.35)
SCHEMBL6313837 0.76 CA2 (0.43) CA1CA2EGFRALDH1A1GAA
SCHEMBL8633313 0.74 HSPA5 (0.39) ALDH1A1MAPT
SCHEMBL8634112 0.73 CA1 (0.37) CA1CA2DRD2DRD1DRD5
SCHEMBL28506063 0.68 CA2 (0.53) CA1CA2EGFRALDH1A1GAA
SCHEMBL8907901 0.67 CNR1 (0.37)
SCHEMBL15180075 0.67 CA1 (0.47) CA1CA2ALDH1A1CYP3A4MAPT
SCHEMBL15180062 0.67 CA1 (0.47) CA1CA2EGFRDRD2DRD1
SCHEMBL4236397 0.66 CA1 (0.42) CA1CA2EGFRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5600032-A OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed