Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380385 | 0.85 | HTT (0.39) | HTTKDM4EHPGDKMT2ASCN9A | |
| SCHEMBL8550666 | 0.78 | HTT (0.34) | HTTKDM4EHPGDSCN9AFFAR4 | |
| SCHEMBL8379345 | 0.77 | HTT (0.39) | HTTKDM4EHPGDKMT2ASCN9A | |
| SCHEMBL8378858 | 0.70 | HTT (0.39) | HTTKDM4EHPGDKMT2ASCN9A | |
| SCHEMBL8380383 | 0.69 | HTR1A (0.35) | HTTKDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL8382692 | 0.69 | HTR1A (0.35) | HTTKDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL8664385 | 0.69 | ALDH1A1 (0.38) | HTTKDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL8380382 | 0.67 | RARG (0.36) | KDM4EHPGDKMT2AALDH1A1RAB9A | |
| SCHEMBL8378976 | 0.66 | HTR1A (0.40) | HTTKMT2ARXFP1ALDH1A1HTR1A | |
| SCHEMBL8379339 | 0.66 | HTR1A (0.36) | HTTKMT2ARXFP1ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |