Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378976 | 0.84 | HTR1A (0.40) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8381832 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8378989 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8379003 | 0.75 | ALDH1A1 (0.36) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8378914 | 0.73 | HTR1A (0.39) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8378992 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8380458 | 0.72 | ALDH1A1 (0.34) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8380385 | 0.71 | HTT (0.39) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8378913 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8382406 | 0.70 | KLK7 (0.38) | NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |