SCHEMBL8634207

SCHEMBL8634207

NC1COC2(CCCCC2)OC1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31757109 0.92
SCHEMBL11820421 0.79
SCHEMBL17470028 0.74 PABPC1 (0.35) PABPC1CTDSP1GAA
SCHEMBL6388243 0.74 PABPC1 (0.39) PABPC1CTDSP1GAA
SCHEMBL29668446 0.74 PABPC1 (0.35) PABPC1CTDSP1GAA
SCHEMBL9737126 0.73
SCHEMBL11819182 0.73 ALDH1A1 (0.31)
SCHEMBL16627352 0.72 PABPC1 (0.34) PABPC1CTDSP1GAA
SCHEMBL6389818 0.70 PABPC1 (0.36) PABPC1CTDSP1GAA
SCHEMBL5745703 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0755390-B1 PROCESS FOR THE PREPARATION OF 5-AMINO-1,3-DIOXANES BRACCO INT BV (NL) 1998-08-19 EP disclosed
US-5770773-A Process for the preparation of 5-amino-1,3-dioxanes ZAMBON GROUP S.P.A. (IT) 1998-06-23 US disclosed
EP-0643055-B1 Proces for the preparation of 5-amino-2,2-dialkyl-1,3-dioxanes ZAMBON SPA (IT) 1997-10-08 EP disclosed
US-5663372-A Process for the preparation of 5-amino-1,3-dioxanes ZAMBON GROUP S.P.A. (IT) 1997-09-02 US disclosed
EP-0755390-A1 PROCESS FOR THE PREPARATION OF 5-AMINO-1,3-DIOXANES ZAMBON GROUP S.p.A. (IT) 1997-01-29 EP disclosed
US-5580993-A Process for the preparation of iopamidol and 5-amino-2,2-dialkyl-1,3-dioxanes ZAMBON GROUP S.P.A. (IT) 1996-12-03 US disclosed
WO-1995028395-A1 PROCESS FOR THE PREPARATION OF 5-AMINO-1,3-DIOXANES ZAMBON GROUP S.P.A. (IT) 1995-10-26 WO disclosed
EP-0643055-A1 Proces for the preparation of 5-amino-2,2-dialkyl-1,3-dioxanes ZAMBON GROUP S.p.A. (IT) 1995-03-15 EP disclosed