SCHEMBL6388243

SCHEMBL6388243

CC1COC2(CCCCC2)OC1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6389818 0.97 PABPC1 (0.36) PABPC1CTDSP1GAA
SCHEMBL10265510 0.92 PABPC1 (0.32) PABPC1CTDSP1
SCHEMBL13347183 0.79 KDM4E (0.34)
SCHEMBL10265509 0.77 GAA (0.31) GAA
SCHEMBL21289837 0.75 MEN1 (0.36)
SCHEMBL12944477 0.75 PABPC1 (0.44) PABPC1CTDSP1GAA
SCHEMBL1768178 0.75 HTR1A (0.30)
SCHEMBL3305308 0.75 PABPC1 (0.44) PABPC1CTDSP1GAA
SCHEMBL12944468 0.75 PABPC1 (0.44) PABPC1CTDSP1GAA
SCHEMBL8634207 0.74 PABPC1 (0.35) PABPC1CTDSP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010081731-A2 DERIVATIVES OF SYRINGOLIN A Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) 2010-07-22 WO disclosed
US-20100081693-A1 THIADIAZOLE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-01 US disclosed
WO-2008032858-A2 THIADIAZOLE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-20 WO disclosed
US-20050282710-A1 Substituted benzoylcyclohexanediones as herbicides BAYER CROPSCIENCE GMBH (DE) 2005-12-22 US disclosed
US-20050282709-A1 Substituted benzoylpyrazoles as herbicides BAYER CROPSCIENCE GMBH (DE) 2005-12-22 US disclosed
EP-0042622-B1 Spiro[2,2,6,6-tetramethyl-piperidine-4,2'-(1',3'-dioxo(ol)an]-derivatives and stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282709-A1 Substituted benzoylpyrazoles as herbicides CBR3, CBR1, CYP1B1 PABPC1 4122/4885CTDSP1 4154/4885GAA 2239/4885
US-20050282710-A1 Substituted benzoylcyclohexanediones as herbicides DDT, CBR1, CBR3 PABPC1 4346/4885CTDSP1 3314/4885GAA 2330/4885
US-20100081693-A1 THIADIAZOLE COMPOUND AND USE THEREOF NR2C2, NR4A3, NR0B2 PABPC1 4258/4885CTDSP1 2879/4885GAA 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.