SCHEMBL8634255

SCHEMBL8634255

CCCCC(CCCC)(CCCC)CCCCCCCC=CCCCCCCCCN

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
EPHX1 P07099 1/20 0.46
SLC6A5 Q9Y345 2/20 0.45
FAAH O00519 3/20 0.42
TRPV1 Q8NER1 1/20 0.42
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
SOAT1 P35610 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1362596 0.87 FAAH (0.54) MEN1KMT2AFAAHTRPV1TP53
SCHEMBL11089446 0.87 FAAH (0.54) MEN1KMT2AFAAHTRPV1TP53
SCHEMBL5874836 0.87 DNM1 (0.60) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL14840324 0.86 SLC6A5 (0.39) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL10837134 0.85 FAAH (0.56) MEN1KMT2AFAAHTRPV1TP53
SCHEMBL7544355 0.85 FAAH (0.56) MEN1KMT2AFAAHTRPV1TP53
SCHEMBL25409164 0.83 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Dectaflur SCHEMBL20875746 0.83 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL11849366 0.83 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL22677777 0.83 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0736130-B1 A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES SHELL INT RESEARCH (NL) 1998-07-15 EP claimed
EP-0736130-A1 A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-10-09 EP claimed
US-5460728-A Using quaternary ammonium compound as inhibitor of hydrate formation SHELL OIL COMPANY (US) 1995-10-24 US claimed
WO-1995017579-A1 A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1995-06-29 WO claimed