Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 13/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080436 | 0.76 | HPGD (0.56) | HPGDCA2KMT2APOLB | |
| SCHEMBL9586021 | 0.76 | HPGD (0.53) | HPGDCA2KMT2A | |
| SCHEMBL10423303 | 0.75 | PARP10 (0.52) | HPGD | |
| SCHEMBL10423304 | 0.75 | PARP10 (0.52) | HPGD | |
| SCHEMBL8634918 | 0.75 | HPGD (0.51) | HPGDCA2KMT2APOLB | |
| SCHEMBL4105896 | 0.74 | HPGD (0.54) | HPGDPOLB | |
| SCHEMBL8636310 | 0.73 | HPGD (0.49) | HPGDCA2KMT2APOLB | |
| SCHEMBL20637564 | 0.73 | HPGD (1.00) | HPGD | |
| SCHEMBL19119345 | 0.73 | HPGD (1.00) | HPGD | |
| SCHEMBL28841579 | 0.72 | HPGD (0.53) | HPGDCA2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |