Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27779371 | 0.98 | HPGD (0.56) | HPGDPOLBCA2EPHX2MIF | |
| SCHEMBL4105896 | 0.85 | HPGD (0.54) | HPGDPOLBEPHX2ALDH1A1 | |
| SCHEMBL8862347 | 0.83 | HPGD (0.47) | HPGDPOLBCA2EPHX2 | |
| SCHEMBL9586021 | 0.83 | HPGD (0.53) | HPGDCA2EPHX2MIFKMT2A | |
| SCHEMBL28841579 | 0.83 | HPGD (0.53) | HPGDPOLBCA2EPHX2KMT2A | |
| SCHEMBL9336422 | 0.82 | HPGD (0.52) | HPGDPOLBCA2EPHX2MAPT | |
| SCHEMBL8634918 | 0.80 | HPGD (0.51) | HPGDPOLBCA2EPHX2KMT2A | |
| SCHEMBL10801546 | 0.78 | CA2 (0.48) | HPGDPOLBCA2EPHX2KMT2A | |
| SCHEMBL8636310 | 0.77 | HPGD (0.49) | HPGDPOLBCA2EPHX2KMT2A | |
| SCHEMBL9079270 | 0.76 | MIF (0.43) | HPGDMIFKMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576332-A | Soft β-drenegic blocking agents | IVAX International GmbH (CH) | 1996-11-19 | — | — | US | disclosed |
| US-5482961-A | Soft β-adrenergic blocking agents | IVAX International GmbH (CH) | 1996-01-09 | — | — | US | disclosed |