Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634918 | 0.91 | HPGD (0.51) | HPGDPPARAALDH1A1KMT2ACA2 | |
| SCHEMBL28841579 | 0.79 | HPGD (0.53) | HPGDALDH1A1KMT2ACA2EPHX2 | |
| SCHEMBL9080436 | 0.77 | HPGD (0.56) | HPGDALDH1A1KMT2ACA2EPHX2 | |
| SCHEMBL9586021 | 0.77 | HPGD (0.53) | HPGDALDH1A1KMT2ACA2EPHX2 | |
| SCHEMBL4105896 | 0.75 | HPGD (0.54) | HPGDALDH1A1EPHX2POLB | |
| SCHEMBL19309189 | 0.75 | PARP10 (0.54) | HPGDEPHX2LTA4H | |
| SCHEMBL8639284 | 0.74 | F2 (0.41) | HPGDCA2EPHX2F2 | |
| SCHEMBL8634258 | 0.73 | HPGD (0.57) | HPGDKMT2ACA2POLB | |
| SCHEMBL8385146 | 0.73 | BCL9 (0.53) | PPARAALDH1A1KMT2ACYP4A11EPHX2 | |
| SCHEMBL9336422 | 0.73 | HPGD (0.52) | HPGDALDH1A1CA2EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |