Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636310 | 0.91 | HPGD (0.49) | HPGDALDH1A1KMT2ACA2CYP4A11 | |
| SCHEMBL28841579 | 0.82 | HPGD (0.53) | HPGDALDH1A1KMT2ACA2POLB | |
| SCHEMBL9080436 | 0.80 | HPGD (0.56) | HPGDALDH1A1KMT2ACA2POLB | |
| SCHEMBL9586021 | 0.79 | HPGD (0.53) | HPGDALDH1A1KMT2ACA2EPHX2 | |
| SCHEMBL4105896 | 0.78 | HPGD (0.54) | HPGDALDH1A1POLBEPHX2 | |
| SCHEMBL8634258 | 0.75 | HPGD (0.57) | HPGDKMT2ACA2POLB | |
| SCHEMBL9336422 | 0.75 | HPGD (0.52) | HPGDALDH1A1CA2POLBEPHX2 | |
| SCHEMBL4544905 | 0.74 | F2 (0.59) | HPGDKMT2ACYP4F2CYP4A11POLB | |
| SCHEMBL9332754 | 0.74 | KMT2A (0.58) | ALDH1A1KMT2ACYP4F2CYP4A11PPARA | |
| SCHEMBL29046738 | 0.73 | PPARA (0.53) | KMT2ACA2CYP4F2CYP4A11PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |