SCHEMBL8633165

SCHEMBL8633165

Clc1cc(Cl)cc(Oc2ccc(OCC=C(Br)Br)c(Cl)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.37
PPARD Q03181 4/20 0.37
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PPARA Q07869 5/20 0.35
PPARG P37231 3/20 0.35
TSHR P16473 2/20 0.34
CARM1 Q86X55 1/20 0.34
PRMT6 Q96LA8 1/20 0.34
STK39 Q9UEW8 1/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632796 0.90 TDP1 (0.41) TDP1PPARDHTR2ASLC6A4PPARA
SCHEMBL8632883 0.89 PPARD (0.39) TDP1PPARDHTR2ASLC6A4PPARA
SCHEMBL8636441 0.88 EPAS1 (0.38) TSHRCARM1PRMT6GAAALDH1A1
SCHEMBL8633930 0.87 TDP1 (0.38) TDP1PPARDHTR2ASLC6A4HSP90AA1
SCHEMBL8632023 0.83 PPARD (0.40) TDP1PPARDHTR2ASLC6A4PPARA
SCHEMBL8638737 0.79 HTR2A (0.43) PPARDHTR2ASLC6A4PPARAPPARG
SCHEMBL8632925 0.78 FFAR1 (0.50) TDP1PPARDHTR2ASLC6A4PPARA
SCHEMBL8635839 0.77 PPARG (0.39) PPARDHTR2ASLC6A4PPARGNPC1
SCHEMBL8633759 0.77 PNLIP (0.38) HTR2ASLC6A4ALDH1A1
SCHEMBL8634547 0.77 HSP90AA1 (0.49) HTR2ASLC6A4HSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed