Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673420 | 0.96 | RAPGEF4 (0.67) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL12367736 | 0.92 | RAPGEF4 (0.56) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL25912039 | 0.88 | RAPGEF4 (0.58) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL379238 | 0.83 | RAPGEF4 (0.63) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL14981731 | 0.83 | POLB (0.64) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL8386481 | 0.82 | NPC1 (0.57) | RAPGEF4NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3476199 | 0.81 | EGFR (0.52) | RAPGEF4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL18583900 | 0.79 | RAPGEF4 (0.52) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL13174486 | 0.78 | APP (0.51) | RAPGEF4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL12377130 | 0.78 | NPC1 (0.62) | RAPGEF4NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840980-A | CHARGE TRANSPORT COMPOUNDS; PHOTORECEPTORS WITH HIGH SENSITIVITY AND DURABILITY | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5707768-A | ELECTROCONDUCTIVE SUBSTRATE HAVING A PHOTOSENSITIVE LAYER CONTAINING A BINDER RESIN, A CHARGE GENERATING MATERIAL OR A SENSITIZING DYE AND A DIAMINE COMPOUND THEREON | HODOGAYA CHEMICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |