SCHEMBL863463

SCHEMBL863463

C=C(c1cccc(CO[Si](C)(C)C(C)(C)C)c1)c1cccc(CO[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.36
MRGPRX4 Q96LA9 8/20 0.36
F2 P00734 4/20 0.35
TP53 P04637 2/20 0.35
PKM P14618 2/20 0.35
NFKB1 P19838 2/20 0.35
NFKB2 Q00653 2/20 0.35
RELA Q04206 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
RAB9A P51151 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
IRAK4 Q9NWZ3 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31393761 1.00 F10 (0.36) F10MRGPRX4F2TP53PKM
SCHEMBL20298753 0.96 F10 (0.40) F10MRGPRX4TP53PKMNFKB1
SCHEMBL10204500 0.88 F10 (0.40) F10MRGPRX4F2SMN1; SMN2RAB9A
SCHEMBL5344756 0.86 IRAK4 (0.34) F10MRGPRX4F2TP53PKM
SCHEMBL7892810 0.85 IRAK4 (0.35) F10MRGPRX4F2TP53PKM
SCHEMBL7900095 0.84 SMN1; SMN2 (0.38) F10MRGPRX4SMN1; SMN2RAB9AIRAK4
SCHEMBL5341608 0.84 MRGPRX4 (0.52) MRGPRX4TP53PKMNFKB1NFKB2
SCHEMBL12095859 0.81 SMN1; SMN2 (0.41) MRGPRX4TP53PKMNFKB1NFKB2
SCHEMBL8320447 0.81 LOXL2 (0.56) MRGPRX4SMN1; SMN2RAB9ATSHR
SCHEMBL840465 0.81 GABRA1 (0.45) PKMNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1923418-B1 STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2016-11-09 EP disclosed
EP-2311900-B1 Star polymer and method for producing the same NIPPON SODA CO (JP) 2015-03-11 EP disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-20120077085-A1 POSITIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE BATTERYAND NON-AQUEOUS ELECTROLYTE BATTERY SAKITANI NOBUHIRO (JP) 2012-03-29 US disclosed
US-7968229-B2 Positive electrode for non-aqueous electrolyte battery and non-aqueous electrolyte battery SANYO ELECTRIC CO., LTD. (JP) 2011-06-28 US disclosed
EP-2311900-A1 Star polymer and method for producing the same Nippon Soda Co., Ltd. (JP) 2011-04-20 EP disclosed
US-20090246630-A1 Positive electrode for non-aqueous electrolyte battery and non-aqueous electrolyte battery NIPPON SODA CO., LTD. (JP) 2009-10-01 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed
EP-1923418-A1 STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2008-05-21 EP disclosed