SCHEMBL8634708

SCHEMBL8634708

O=C(O)CCCC(CC1CC=CCC1)(CC1CC=CCC1)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.34
ALDH1A1 P00352 7/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 3/20 0.34
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
PKM P14618 1/20 0.32
ITGB3 P05106 2/20 0.31
ITGA2B P08514 2/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9182805 0.76 KDM4E (0.39) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL15281924 0.73 ALOX5 (0.30)
SCHEMBL27953679 0.73 KDM5A (0.44) KDM4EALDH1A1MEN1KMT2ATDP1
SCHEMBL9183918 0.72 KDM4E (0.41) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL23319670 0.71 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL134571 0.70 TBXA2R (0.33) KDM4EITGB3ITGA2BTP53TSHR
SCHEMBL15658730 0.70 ITGB3 (0.30) ITGB3ITGA2B
SCHEMBL8202305 0.69 LMNA (0.53) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL28357278 0.69 LMNA (0.47) KDM4EALDH1A1MEN1KMT2ATDP1
Adipic Acid SCHEMBL30510690 0.69 ITGB3 (0.35) CYP2D6ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013143881-A1 CARBOXYLIC ESTER OR POLYETHER ESTER AS PROCESSING AID FOR FLUORO RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2013-10-03 WO claimed
EP-2644648-A1 Carboxylic acid esters or polyetheresters as a processing aid for fluoro-rubbers LANXESS Deutschland GmbH (DE) 2013-10-02 EP claimed
WO-2013143881-A1 CARBOXYLIC ESTER OR POLYETHER ESTER AS PROCESSING AID FOR FLUORO RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2013-10-03 WO disclosed
EP-2644648-A1 Carboxylic acid esters or polyetheresters as a processing aid for fluoro-rubbers LANXESS Deutschland GmbH (DE) 2013-10-02 EP disclosed
EP-0655472-B1 Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENIRICERCHE SPA (IT) 1998-07-29 EP disclosed
EP-0546602-B1 Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM SPA (IT) 1996-07-24 EP disclosed
US-5489664-A Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENICHEM S.P.A. (IT) 1996-02-06 US disclosed
EP-0454207-B1 Liquid, reactive compositions endowed with high polymerization speed, containing polyisocyanates and compounds with one or more epoxy groups ENICHEM SPA (IT) 1995-11-02 EP disclosed
EP-0655472-A1 Microwave-polymerizable isocyanate/epoxy resins for heavy-duty applications ENIRICERCHE S.p.A. (IT) 1995-05-31 EP disclosed
US-5326833-A Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM S.P.A. (IT) 1994-07-05 US disclosed
EP-0598433-A2 Process for curing polymerizable liquid compositions based on polyisocyanates and epoxides ENICHEM S.p.A. (IT) 1994-05-25 EP disclosed
US-5314983-A Process for curing polymerizable liquid compositions based on polyisocyanates and epoxides ENICHEM S.P.A. (IT) 1994-05-24 US disclosed
EP-0546602-A1 Liquid reactive compositions comprising polyisocyanates, epoxides and solutions of alkali metal halides in polyoxyalkylenic compounds ENICHEM S.p.A. (IT) 1993-06-16 EP disclosed
US-5145880-A LIQUID, REACTIVE COMPOSITIONS ENDOWED WITH HIGH POLYMERIZATION SPEED, CONTAINING POLYISOCYANATES AND COMPOUNDS WITH ONE OR MORE EPOXY GROUPS ENICHEM S.P.A. (IT) 1992-09-08 US disclosed
EP-0454207-A1 Liquid, reactive compositions endowed with high polymerization speed, containing polyisocyanates and compounds with one or more epoxy groups ENICHEM S.p.A. (IT) 1991-10-30 EP disclosed