Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8638110 | 0.92 | F2 (0.46) | F2ALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL8636416 | 0.83 | F2 (0.43) | F2ALDH1A1KMT2ARAB9ATSHR | |
| SCHEMBL2720399 | 0.77 | RAB9A (0.57) | ALDH1A1SMN1; SMN2KMT2ARAB9ATSHR | |
| SCHEMBL31445349 | 0.77 | RAB9A (0.57) | ALDH1A1SMN1; SMN2KMT2ARAB9ATSHR | |
| Hydrochloric Acid SCHEMBL11349059 | 0.75 | RAB9A (0.56) | ALDH1A1SMN1; SMN2KMT2ARAB9ATSHR | |
| SCHEMBL25398545 | 0.74 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL7297481 | 0.73 | ALDH1A1 (0.55) | F2ALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL7303285 | 0.73 | PREP (0.54) | F2ALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL7303289 | 0.73 | PREP (0.54) | F2ALDH1A1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL7295630 | 0.73 | F2 (0.60) | F2ALDH1A1SMN1; SMN2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760235-A | DIPEPTIDES BASED ON PROLINE OR PIPECOLIC ACID AND ARGININE ALDEHYDE | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1998-06-02 | — | — | US | disclosed |
| EP-0629212-B1 | NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF | GYOGYSZERKUTATO INTEZET (HU) | 1997-10-08 | — | — | EP | disclosed |
| EP-0629212-A1 | NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF. | GYOGYSZERKUTATO INTEZET (HU) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993018060-A1 | NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF | Gyógyszerkutató Intézet Kft. (HU) | 1993-09-16 | — | — | WO | disclosed |