Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282581 | 0.93 | ALDH1A1 (0.71) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4397337 | 0.90 | TSHR (0.61) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL1283321 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL1598666 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1MAPK1LMNA | |
| SCHEMBL1282684 | 0.84 | TSHR (0.73) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL1283310 | 0.83 | TSHR (0.69) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4394455 | 0.83 | HSD17B10 (0.56) | ALDH1A1TSHRTDP1L3MBTL1LMNA | |
| SCHEMBL4393206 | 0.82 | TSHR (0.50) | ALDH1A1TSHRTDP1L3MBTL1LMNA | |
| SCHEMBL5155541 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 | |
| SCHEMBL4782034 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRTDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360578-B1 | Process for the production of polycarbonates | GE PLASTICS JAPAN LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5276129-A | Aromatic polycarbonates with excellent color tone, heat resistance and water resistance | GE PLASTICS JAPAN, LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| US-5151491-A | Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol | GE PLASTICS JAPAN, LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0360578-A2 | Process for the production of polycarbonates | GE PLASTICS JAPAN LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |