Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | GGT1 | P19440 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861110 | 1.00 | ALDH1A1 (0.69) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL11985691 | 0.92 | PTGS2 (0.68) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL1870045 | 0.91 | TSHR (0.71) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL27528077 | 0.89 | TSHR (0.71) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL11985699 | 0.89 | PTGS2 (0.72) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL1282581 | 0.89 | ALDH1A1 (0.71) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL4732320 | 0.88 | ALDH1A1 (0.72) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL11314352 | 0.88 | ALDH1A1 (0.72) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL4730460 | 0.88 | ALDH1A1 (0.72) | ALDH1A1PTGS2KDM4EHSD17B10LMNA | |
| SCHEMBL4728781 | 0.88 | ALDH1A1 (0.72) | ALDH1A1PTGS2KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101890167-A | Conveniently implantable sustained release drug compositions | RAMSCOR INC | 2010-11-24 | — | — | CN | disclosed |
| CN-101060831-B | Conveniently implantable sustained release pharmaceutical composition | RAMSCOR INC | 2010-06-23 | — | — | CN | disclosed |
| US-20090137532-A1 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2009-05-28 | — | — | US | disclosed |
| US-20090137532-A1 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2009-05-28 | — | — | US | disclosed |
| US-7470821-B2 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2008-12-30 | — | — | US | disclosed |
| US-7470821-B2 | Aldolase-inhibiting aromatic compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2008-12-30 | — | — | US | disclosed |
| EP-1641807-B1 | AROMATIC COMPOUNDS AS ALDOLASE INHIBITORS | UNIV TOULOUSE (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008043654-A2 | BLOND CLEAR TREATMENT | HENKEL AG & CO. KGAA (DE) | 2008-04-17 | — | — | WO | disclosed |
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2007-02-22 | — | — | US | disclosed |
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | UNIVERSITE PAUL SABATIER TOULOUSE III (FR) | 2007-02-22 | — | — | US | disclosed |
| CN-1144092-A | Non-steroid anti-inflammatory agents capable of releasing nitric oxide, their preparing method and use | CAI XIONG (CN) | 1997-03-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043002-A1 | Aldolase-inhibiting aromatic compounds | ALDOA, DERA, AKR1B1 | ALDH1A1 17/4885PTGS2 2077/4885KDM4E 828/4885 |
| US-20090137532-A1 | Aldolase-inhibiting aromatic compounds | ALDOA, DERA, AKR1B1 | ALDH1A1 17/4885PTGS2 2077/4885KDM4E 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.