Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.83 |
| ▸ | MMP3 | P08254 | 14/20 | 0.83 |
| ▸ | MMP1 | P03956 | 6/20 | 0.67 |
| ▸ | MMP7 | P09237 | 3/20 | 0.67 |
| ▸ | MMP9 | P14780 | 3/20 | 0.67 |
| ▸ | MMP14 | P50281 | 1/20 | 0.66 |
| ▸ | BMP1 | P13497 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092582 | 1.00 | MMP2 (0.83) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL8094644 | 1.00 | MMP2 (0.83) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL8086477 | 1.00 | MMP2 (0.83) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL8602112 | 0.88 | MMP2 (0.65) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL8625367 | 0.88 | MMP2 (0.65) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL8101473 | 0.85 | MMP2 (0.65) | MMP2MMP3MMP1MMP9BMP1 | |
| SCHEMBL8397206 | 0.82 | MMP3 (0.79) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL8080977 | 0.81 | MMP2 (0.56) | MMP2MMP3MMP1MMP7 | |
| SCHEMBL14545737 | 0.81 | MMP3 (1.00) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL8398532 | 0.81 | MMP3 (1.00) | MMP2MMP3MMP1MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821666-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033161-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-24 | — | — | WO | disclosed |