Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 14/20 | 0.79 |
| ▸ | MMP2 | P08253 | 12/20 | 0.79 |
| ▸ | MMP1 | P03956 | 11/20 | 0.79 |
| ▸ | MMP7 | P09237 | 5/20 | 0.79 |
| ▸ | MMP9 | P14780 | 3/20 | 0.79 |
| ▸ | Q9HBH1 | 1/20 | 0.64 | |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398532 | 0.88 | MMP3 (1.00) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL14545737 | 0.88 | MMP3 (1.00) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8396712 | 0.87 | MMP3 (0.79) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8055018 | 0.87 | MMP3 (0.78) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8400266 | 0.86 | MMP3 (0.77) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8397183 | 0.84 | PDF (0.90) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL7070053 | 0.82 | MMP3 (0.80) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL7070048 | 0.82 | MMP3 (0.80) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8094644 | 0.82 | MMP2 (0.83) | MMP3MMP2MMP1MMP7MMP9 | |
| SCHEMBL8634826 | 0.82 | MMP2 (0.83) | MMP3MMP2MMP1MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | claimed |